Panel 1: methodological issues in pharmacoeconomic evaluations--clinical studies.

Panel 3: methodological issues in conducting pharmacoeconomic evaluations--retrospective and claims database studies.

Pharmacoeconomic analyses can be conducted within the context of clinical studies or by using retrospective databases. Randomized clinical trials (RCTs) and observational studies, specifically retrospective database analyses, answer different questions. For example, most RCTs are designed to measure efficacy, not effectiveness. Existing databases can provide effectiveness and “real-world” data....

Haemophilia A: Pharmacoeconomic Review of Prophylaxis Treatment versus On-Demand

OBJECTIVES Haemophilia A is a congenital disorder of coagulation that mainly affects males and causes a considerable use of resources, especially when hemophilic patients are treated with prophylaxis. The aim of the present review was to discuss and appraise the methodological aspects and results of published economic evaluations of haemophilia A treatments in the last decade. METHODS The lit...

Panel 2: methodological issues in conducting pharmacoeconomic evaluations--modeling studies.

The primary purpose of modeling is to inform the decision-making process [1,2]. One considerable benefit of model formalization is that the uncertainties and assumptions in this process are made explicit and transparent. To estimate costs and outcomes, existing data are frequently insufficient to allow optimal healthcare decision-making. Each type of data (retrospective, prospective, meta-analy...

Guidelines of Methodological Standards for Pharmacoeconomic Evaluations in Taiwan

Achieving Consensus Deal with Methodological Issues in the Delphi Technique

Delphi is a powerful technique used to seek answers to appropriate questions. The purpose of this paper is to provide an overview of the Delphi technique as a research method. This paper discusses the scientific merit of the Delphi technique by investigating on 41 studies of Journal of Agricultural Education from 1981 to 2013, and 2 studies of Journal of Agricultural Science and Technology. The...